Split string, ignoring Case,ignoring blank values and Select Distinct split values

String str = "ankit,Ankit,ankit, , ,aNkit,rahul";

here, we have to split above string  by ','


var split_values = str.Split(new char[] { ',' }, StringSplitOptions.RemoveEmptyEntries).Distinct(StringComparer.CurrentCultureIgnoreCase); 



You will get :

ankit
rahul